- The behind-the-scenes story detailing the search for a transformative cure for cancer will unfold on screen at the Tribeca Film Festival.
- The film is an emotional journey that reveals decades of research, and the last hopes of a young patient’s family to save their daughter.
- Which culminated in the world’s first CAR T-cell therapy.
The behind-the-scenes story detailing the search for a transformative cure for cancer will take place on screen Tribeca Film Festival in New York City this weekend; “Of Medicine and Miracles”, which will premiere during the renowned international festival.
The movie is a emotional journey that reveals decades of research, and the last hopes of a young patient’s family to save their daughterculminating in the world’s first CAR T-cell therapy, an approach that reprograms patients’ own immune cells to kill their cancer.
From the award-winning director Oscar RossKauffman and from Oscar-nominated producer Robin Honan, the documentary follows three paths that come together in what became a pivotal moment in cancer history.
The movie narrates the life and work of the doctor and scientist Carl June, MD, whose vision paved the way for revolutionary therapy, and the team of physicians and researchers at Penn Medicine and Children’s Hospital of Philadelphia (CHOP) who joined forces on lab benches and hospital beds to designing the bold approach to treating patients left without conventional options.
The family waiting for a miracle to save a life
Their paths crossed in 2012 with Emily Whitehead, a six-year-old leukemia patient, whose family was hoping for a miracle for her. save lifes when they joined the clinical trial at CHOP that would make her the lthe first girl to receive the experimental treatment, which had previously been tested in only a small handful of adults at Penn Medicine’s Abramson Cancer Center.
Tribeca Film Festival director Cara Cusumano called the film “a moving record of medical history that honors its subjects and their trauma while empowering future generations to attempt the impossible.”
“Of Medicine and Miracles” took 10 years to develop, beginning with the 2012 short film “Fire with Fire,” which went viral after being posted on Upworthy, a website dedicated to positive storytelling.
In addition to Carl June, who is the director of the Center for Cellular Immunotherapies and the Richard W. Vague Professor in Immunotherapy, “Of Medicine and Miracles” also features Bruce Levine, PhD of Penn Medicine, the Barbara and Edward Netter Professor in Cancer Gene Therapy and the Founding Director of Clinical Cell and Vaccine Production Facility, and David Porter, MD, Director of Cell Therapy and Transplantation at the Abramson Cancer Center and Professor Jodi Fischer Horowitz in Leukemia Care Excellence. L
Physicians at Children’s Hospital of Philadelphia, Stephan Grupp, MD, PhD, Section Chief of Cell Therapy and Transplantation and Inaugural Director of the Susan S. and Stephen P. Kelly Center for Cancer Immunotherapy, and Susan Rheingold, MD, Director Medical Oncology Outpatient consultations are also highlighted.
Kauffman’s documentary film credits include “Born into Burthels,” “E-TEAM” and the Oscar-winning “Tigerland.” Honan received an Oscar nomination for the documentary “Mondays at Racine” and co-produced the Oscar-winning “Freeheld.”
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