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According to Statista, during 2017 it was discovered that 82% of people who suffer from migraines missed regular work days because of them.
According to Statista, in 2017, 38% of respondents diagnosed with migraines believed that migraines had specific biological causes.
According to Statista, 38% of respondents diagnosed with migraines believed migraines had specific biological causes in 2017.
According to the findings of the genetic analyzes of a study Conducted by Professor Dale Nyholt and his PhD candidates Hamzeh Tanha and Anita Sathyanarayanan, all from the QUT Center for Genomics and Individualized Health have identified that migraines may be caused by alterations in metabolites.
Professor Nyholt said the team identified causal genetic links to three levels of metabolites in the blood that increase the risk of migraines: lower levels of DHA, an omega-3 known to reduce inflammation, higher levels of LPE (20 :4), a chemical that blocks an anti-inflammatory molecule, lower levels of a third, currently uncharacterized metabolite called X-11315.
Professor Nyholt said these genetic links could now be the subject of further research or clinical trials with the aim of developing and testing compounds that influence metabolite levels to prevent migraine.
He said migraine is estimated to cost the Australian economy $35.7 billion each year and current treatments fail in up to 50 percent of migraine sufferers.
“The observed relationships between genetic factors influencing blood metabolite levels and genetic risk for migraine suggest altered metabolites in people with migraine,” said Professor Nyholt.
Metabolites are substances that are made or used when the body breaks down foods, drugs, or chemicals during metabolism.
“Variations in blood metabolite levels can be due to diet, lifestyle and genetics, but they are easy to measure and can be modified through diet planning and supplementation,” said Professor Nyholt.
Professor Nyholt said that people with migraine had higher levels of shorter-length fatty acids, except for docosahexaenoic acid (DHA), a very long-chain omega-3 that protects against migraine.
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