The IARC classified aspartame as “possibly carcinogenic to humans” due to “limited evidence” of its carcinogenicity in humans. Meanwhile, other organizations maintained the acceptable daily intake of 40 mg/kg body weight for aspartame.
Additionally, previous research from the Florida State University College of Medicine had suggested a possible relationship between aspartame consumption and deficits in learning and memory in mice.
More research is needed
Although this study does not establish a direct causal relationship, it highlights the need for further research in this area, the authors noted.
Additional studies with larger samples and prospective measurements of dietary exposures and other risk factors are required. Furthermore, it is critical to determine whether these associations extend to the risk of autism spectrum disorder in all children.
Aspartame has been the subject of controversy since its discovery due to concerns about its carcinogenic potential, its relationship to diabetes and premature birth. However, regulatory authorities have established safe limits on its consumption.