{"id":221598,"date":"2022-01-11T05:33:01","date_gmt":"2022-01-11T00:03:01","guid":{"rendered":"https:\/\/www.www.bullfrag.com\/what-is-butterfly-skin-2\/"},"modified":"2022-01-11T05:33:01","modified_gmt":"2022-01-11T00:03:01","slug":"what-is-butterfly-skin-2","status":"publish","type":"post","link":"https:\/\/www.bullfrag.com\/what-is-butterfly-skin-2\/","title":{"rendered":"What is butterfly skin?"},"content":{"rendered":"<div id=\"\">\n<div class=\"article-info  mtb--normal lh--1-5 c--main-800 d--flex ai--center\"> <button type=\"button\" on=\"tap:modal-fast-check.toggleClass(class='modal--show'),modal__overlay-fast-check.toggleClass(class='modal--show'),modal__overlay-fast-check.toggleClass(class='fade')\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Post&quot;,&quot;label&quot;:&quot;Fact Checked&quot;}}\" class=\"jsx-4253091997 button jsx-4043901426 jsx-2851335579 button__background-color button__text-color has--border c--main-800 bc--transparent is--custom  has--icon d--flex ai--center jc--center pl--0 mr--x-big\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" focusable=\"false\" style=\"transform:rotate(360deg);vertical-align:-0.125em\" class=\"iconify jsx-1930766275 mr--small\" width=\"16px\" height=\"16px\" preserveaspectratio=\"xMidYMid meet\" viewbox=\"0 0 24 24\"><path d=\"M12 2C6.486 2 2 6.486 2 12s4.486 10 10 10s10-4.486 10-10S17.514 2 12 2zm0 18c-4.411 0-8-3.589-8-8s3.589-8 8-8s8 3.589 8 8s-3.589 8-8 8z\" fill=\"#aecf61\"\/><path d=\"M9.999 13.587L7.7 11.292l-1.412 1.416l3.713 3.705l6.706-6.706l-1.414-1.414z\" fill=\"#aecf61\"\/><\/svg><span class=\"fs--small lh--1-7 ff--serif ta--left\">Fact checked<\/span><\/button><\/p>\n<div class=\"modal__group jsx-526223642 jsx-3159152102 zi--11\">\n<div class=\"modal modal-size jsx-526223642 jsx-3159152102  false  bc--white br--small w--50\" id=\"modal-fast-check\">\n<div class=\"modal__content jsx-526223642 jsx-3159152102 mlr--auto mtb--0 p--relative zi--11\"><button type=\"button\" class=\"jsx-4253091997 button jsx-4043901426 jsx-2851335579 button__background-color button__text-color has--border c--main-800 bc--transparent is--normal  has--icon d--flex ai--center jc--center is--action modal__button jsx-526223642 jsx-3159152102 p--absolute t--0 r--0\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" focusable=\"false\" style=\"transform:rotate(360deg)\" class=\"iconify jsx-3637462050 \" width=\"24px\" height=\"24px\" preserveaspectratio=\"xMidYMid meet\" viewbox=\"0 0 24 24\"><path d=\"M16.192 6.344l-4.243 4.242l-4.242-4.242l-1.414 1.414L10.535 12l-4.242 4.242l1.414 1.414l4.242-4.242l4.243 4.242l1.414-1.414L13.364 12l4.242-4.242z\" fill=\"#000\"\/><\/svg><\/button><span class=\"jsx-3692753319 fs--normal fw--bold lh--1-5 ls--big ff--sans d--block p--x-big c--main-800\">The article has been verified to ensure the highest possible accuracy (content includes links to reputable media sites, academic research institutions, and occasionally medical studies).  All content on our website has been reviewed, however, if you consider that our content is inaccurate, outdated or questionable, you can <strong>contact us<\/strong> to make the necessary corrections.<\/span><\/div>\n<\/div>\n<\/div>\n<p><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" focusable=\"false\" style=\"transform:rotate(360deg);vertical-align:-0.125em\" class=\"iconify jsx-1930766275 mr--small\" width=\"16px\" height=\"16px\" preserveaspectratio=\"xMidYMid meet\" viewbox=\"0 0 24 24\"><path d=\"M12 5c-4.411 0-8 3.589-8 8s3.589 8 8 8s8-3.589 8-8s-3.589-8-8-8zm0 14c-3.309 0-6-2.691-6-6s2.691-6 6-6s6 2.691 6 6s-2.691 6-6 6z\" fill=\"#486db7\"\/><path d=\"M11 9h2v5h-2zM9 2h6v2H9zm10.293 5.707l-2-2l1.414-1.414l2 2z\" fill=\"#486db7\"\/><\/svg> <span class=\"fs--small lh--1-7 ff--serif ta--left\">5 minutes<\/span><\/div>\n<div class=\"excerpt-image d--flex jsx-3361092747\">\n<p>Butterfly skin is the generic name for a group of skin conditions.  We show you their types, characteristics and treatment. <\/p>\n<figure class=\"jsx-2644691033 figure jsx-2087436269 is--full-width  excerpt-image__figure jsx-3361092747 d--block of--cover mtb--x-medium p--relative\">\n<div class=\"jsx-2644691033 image__container jsx-2087436269\"><noscript><\/noscript><\/p>\n<div style=\"display:block;overflow:hidden;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;margin:0\"><img alt=\"What is butterfly skin?\" style=\"position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:cover\" title=\"\" sizes=\"100vw\" srcset=\"https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=640&amp;crop=16:9,smart,safe 640w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=750&amp;crop=16:9,smart,safe 750w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=828&amp;crop=16:9,smart,safe 828w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=1080&amp;crop=16:9,smart,safe 1080w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=1200&amp;crop=16:9,smart,safe 1200w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=1920&amp;crop=16:9,smart,safe 1920w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=2048&amp;crop=16:9,smart,safe 2048w, https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=3840&amp;crop=16:9,smart,safe 3840w\" src=\"https:\/\/mejorconsalud.as.com\/wp-content\/uploads\/2022\/01\/dermatologo-piel-enfermedad-consulta-768x512.jpg?auto=webp&amp;quality=45&amp;width=3840&amp;crop=16:9,smart,safe\" decoding=\"async\" class=\"figure__image jsx-2087436269 w--100 h--100 d--block p--relative\"><\/div>\n<\/div>\n<\/figure>\n<\/div>\n<div class=\"jsx-863588608 hidden-desktop\">\n<div class=\"article-revision mtb--normal\">\n<div class=\"d--flex ai--flex-start\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" focusable=\"false\" style=\"transform:rotate(360deg);vertical-align:-0.125em\" class=\"iconify jsx-1930766275 mt--normal mr--normal\" width=\"16px\" height=\"16px\" preserveaspectratio=\"xMidYMid meet\" viewbox=\"0 0 24 24\"><path d=\"M19 4h-2V2h-2v2H9V2H7v2H5c-1.103 0-2 .897-2 2v14c0 1.103.897 2 2 2h14c1.103 0 2-.897 2-2V6c0-1.103-.897-2-2-2zm.002 16H5V8h14l.002 12z\" fill=\"#d4649a\"\/><path d=\"M11 17.414l5.707-5.707l-1.414-1.414L11 14.586l-2.293-2.293l-1.414 1.414z\" fill=\"#d4649a\"\/><\/svg><\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800 fs--small  lh--1-7 ptb--small\"><strong>Last update:<\/strong> <!-- -->January 08, 2022<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">Butterfly skin, also known as<em> epidermolysis bullosa<\/em> or <em>epidermolysis bullosa<\/em>, is the name given to a group of diseases that are characterized by the fragility of the skin. <strong>It is a very rare skin disorder that only affects a few thousand people worldwide.<\/strong>.  We show you what it is, what its types are and what options exist to treat it.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">In accordance with <a href=\"https:\/\/link.springer.com\/article\/10.1186\/1750-1172-5-12\" data-with-google-events=\"true\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Content&quot;,&quot;label&quot;:&quot;Related \/piel-mariposa\/&quot;,&quot;value&quot;:&quot;https:\/\/link.springer.com\/article\/10.1186\/1750-1172-5-12&quot;}}\" target=\"_blank\" rel=\"noopener nofollow\" class=\"jsx-151512268 jsx-2827724237 default-a-link is--underline c--secondary-600 is--underline\">the researchers<\/a>, <strong>in the United States only 19 cases per million inhabitants are reported<\/strong>.  The symptoms are very varied, also its evolution.  It is one of the most enigmatic conditions, although this does not imply a total ignorance on the part of scientists.  In the following lines we show you everything you should know about butterfly skin.<\/p>\n<h2 id=\"caracteristicas-de-la-piel-de-mariposa\" class=\"jsx-3692753319 jsx-2566528898 c--main-600  mt--x-big pt--normal\">Butterfly skin characteristics<\/h2>\n<figure class=\"jsx-2644691033 figure jsx-2087436269 is--full-width  mt--normal mb--normal p--relative\"><figcaption class=\"jsx-2644691033 ff--sans bc--grey-cold-50 c--grey-cold-500 p--normal lh--1-5\">Although the characteristic lesions of epidermolysis bullosa are blisters, these patients have a tendency to develop various skin problems.<\/figcaption><\/figure>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">As indicated <a href=\"https:\/\/www.nature.com\/articles\/s41572-020-0210-0\" data-with-google-events=\"true\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Content&quot;,&quot;label&quot;:&quot;Related \/piel-mariposa\/&quot;,&quot;value&quot;:&quot;https:\/\/www.nature.com\/articles\/s41572-020-0210-0&quot;}}\" target=\"_blank\" rel=\"noopener nofollow\" class=\"jsx-151512268 jsx-2827724237 default-a-link is--underline c--secondary-600 is--underline\">The experts<\/a>, butterfly skin is characterized by mucocutaneous fragility that is accompanied by blisters that develop due to minimal trauma.  Indeed, lesions can appear from harmless actions such as exposure to the sun for a few minutes, rubbing the skin with an object, scratching or using adhesive tape.<\/p>\n<hr class=\"jsx-1495579005 divider w--100 is--normal \"\/>\n<hr class=\"jsx-1495579005 divider w--100 is--normal \"\/>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">According to the level of separation of the tissues, <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1346-8138.2009.00800.x\" data-with-google-events=\"true\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Content&quot;,&quot;label&quot;:&quot;Related \/piel-mariposa\/&quot;,&quot;value&quot;:&quot;https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1346-8138.2009.00800.x&quot;}}\" target=\"_blank\" rel=\"noopener nofollow\" class=\"jsx-151512268 jsx-2827724237 default-a-link is--underline c--secondary-600 is--underline\">the scientists<\/a> distinguish three types of butterfly skin: <strong>simple, junctional, and dystrophic<\/strong>.  Let&#8217;s briefly see the characteristics of these:<\/p>\n<ul class=\"jsx-1463435145 list-on-content mlr--x-big mtb--big c--grey-neutral-800 lh--1-8 ff--serif lst--disc\">\n<li><strong>Simple epidermolysis bullosa: <\/strong>it is the most frequent variant of all.  It usually only affects the palms and soles, and it always does so on the outer layer (epidermis).  The blisters are usually mild and when they heal they do not leave visible scars.<\/li>\n<\/ul>\n<ul class=\"jsx-1463435145 list-on-content mlr--x-big mtb--big c--grey-neutral-800 lh--1-8 ff--serif lst--disc\">\n<li><strong>Junctional epidermolysis bullosa: <\/strong>patients who develop this type of butterfly skin do so from childhood with serious injuries.  It affects collagen and laminin, so it can affect the entire body (joints, hands, feet, and so on).  It is not uncommon for children to develop vocal cord blisters with this variant.<\/li>\n<li><strong>Dystrophic epidermolysis bullosa: <\/strong>It manifests itself due to the absence of a gene that contributes a type of collagen that the skin requires to acquire strength.  It has two main subtypes: Pasini&#8217;s disease and pruritic epidermolysis bullosa.<\/li>\n<\/ul>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">Most cases of butterfly skin are inherited, although <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0738081X11000873\" data-with-google-events=\"true\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Content&quot;,&quot;label&quot;:&quot;Related \/piel-mariposa\/&quot;,&quot;value&quot;:&quot;https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0738081X11000873&quot;}}\" target=\"_blank\" rel=\"noopener nofollow\" class=\"jsx-151512268 jsx-2827724237 default-a-link is--underline c--secondary-600 is--underline\">the evidence indicates<\/a> that can also be purchased.  Apart from this, having a family history of the disease potentially increases the chances of developing it in childhood or at some point in life.<\/p>\n<h2 id=\"sintomas-de-la-epidermolisis-bullosa\" class=\"jsx-3692753319 jsx-2566528898 c--main-600  mt--x-big pt--normal\">Symptoms of epidermolysis bullosa<\/h2>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">Butterfly skin is a very heterogeneous condition.  Not only because the clinical picture of the three types is different, <strong>but because patients with the same variant do not develop it with the same intensity or signs<\/strong>.  In general, we highlight the following symptoms of epidermolysis bullosa:<\/p>\n<ul class=\"jsx-1463435145 list-on-content mlr--x-big mtb--big c--grey-neutral-800 lh--1-8 ff--serif lst--disc\">\n<li>Fragile skin that breaks and blisters easily (with slight friction with an object, even with a change in temperature).<\/li>\n<li>Blisters inside the oral cavity or throat.<\/li>\n<li>Malformation of the nails of the feet and hands (they are usually thicker).<\/li>\n<li>Thick skin, especially on the hands and feet.<\/li>\n<li>Itching and burning on the surface of the skin.<\/li>\n<li>Atrophic scarring after the blisters have disappeared.<\/li>\n<li>Blisters on the scalp.<\/li>\n<\/ul>\n<ul class=\"jsx-1463435145 list-on-content mlr--x-big mtb--big c--grey-neutral-800 lh--1-8 ff--serif lst--disc\">\n<li>Swallowing problems (dysphagia).  This can evolve into malnutrition due to rejection of food.<\/li>\n<li>Recurring infections due to exposure of the blisters.<\/li>\n<\/ul>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">These are the general symptoms of butterfly skin, although of course many more can develop.  For example, constipation, joint pain, malformation of the fingers and toes (they can join in the scarring), septicemia and so on.<\/p>\n<hr class=\"jsx-1495579005 divider w--100 is--normal \"\/>\n<hr class=\"jsx-1495579005 divider w--100 is--normal \"\/>\n<h2 id=\"diagnostico-de-la-piel-de-mariposa\" class=\"jsx-3692753319 jsx-2566528898 c--main-600  mt--x-big pt--normal\">Butterfly skin diagnosis<\/h2>\n<figure class=\"jsx-2644691033 figure jsx-2087436269 is--full-width  mt--normal mb--normal p--relative\"><figcaption class=\"jsx-2644691033 ff--sans bc--grey-cold-50 c--grey-cold-500 p--normal lh--1-5\">The best method to make an accurate diagnosis is through a skin biopsy.  Occasionally, an immunohistochemical study may be necessary.<\/figcaption><\/figure>\n<p class=\"jsx-4098198752 c--grey-neutral-800\"><strong>Butterfly skin is a very rare disease<\/strong>, and mild cases are often easily confused with other types of skin pathologies.  The standard procedure for its diagnosis is to perform a skin biopsy for immunofluorescent mapping.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">It is a procedure in which a sample of skin is removed from the affected area to examine it in a special way, so that the different layers of the skin can be appreciated.  This type of biopsy also makes it possible to identify the proteins involved in these analyzed layers.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">If the condition is suspected to be hereditary, <strong>the specialist will also perform genetic tests<\/strong>.<\/p>\n<h2 id=\"tratamiento-para-la-epidermolisis-bullosa\" class=\"jsx-3692753319 jsx-2566528898 c--main-600  mt--x-big pt--normal\">Treatment for epidermolysis bullosa<\/h2>\n<p class=\"jsx-4098198752 c--grey-neutral-800\"><strong>There is currently no cure for butterfly skin<\/strong>.  However, there are a couple of options available to make the condition much more tolerable for patients.  In principle, it all depends on the severity with which it has developed and the long-term forecasts.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">For example, small changes in day-to-day habits such as wearing looser clothes, modifying your diet or being careful with household chores may be sufficient in mild cases.  For moderate or severe cases, the intake of medications is preferred, especially to treat wounds that can evolve into infections and pain.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/exd.13979\" data-with-google-events=\"true\" data-google-events=\"{&quot;data&quot;:{&quot;action&quot;:&quot;click&quot;,&quot;category&quot;:&quot;Content&quot;,&quot;label&quot;:&quot;Related \/piel-mariposa\/&quot;,&quot;value&quot;:&quot;https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/exd.13979&quot;}}\" target=\"_blank\" rel=\"noopener nofollow\" class=\"jsx-151512268 jsx-2827724237 default-a-link is--underline c--secondary-600 is--underline\">The scientists<\/a> they are investigating alternative treatment options for the future, such as protein replacement therapy and bone marrow transplantation.  Some patients require surgery to widen the esophagus, restore mobility, skin grafts, and even intervention with feeding tubes. <strong>They must also learn to heal and bandage wounds<\/strong>.<\/p>\n<p class=\"jsx-4098198752 c--grey-neutral-800\">Although at the moment the options are limited, it is expected that in a couple of decades there will be treatment alternatives that will reduce the symptoms and the progression of the disease.  At the moment it is recommended to seek medical assistance before the development of symptoms, so you can choose to start a treatment depending on the intensity and type of variant manifested.<\/p>\n<p><span class=\"jsx-284598183 fs--xx-medium fw--bold lh--1-2 ls--medium ff--sans d--block ta--left pb--normal c--grey-neutral-600  has--divider-dashed\">It might interest you &#8230;<\/span><\/div>\n<p><script type=\"application\/json\" id=\"mc-loader-data\">{\"scripts\":[{\"src\":\"https:\/\/www.googletagmanager.com\/gtag\/js?id=UA-36759908-1\",\"debugMessage\":\"GTag UA-36759908-1\",\"defer\":true,\"async\":true,\"id\":\"googletagmanager-UA-36759908-1\",\"lazy\":false,\"lazyType\":\"both\"},{\"text\":\"n      window.dataLayer = window.dataLayer || [];n      function gtag(){dataLayer.push(arguments);}n      gtag('js', new Date());n      gtag('config', 'UA-36759908-1', {\"content_group1\":\"Article\",\"anonymizeIp\":true,\"cookie_expires\":31536000});n      \",\"type\":\"didomi\/javascript\",\"async\":true,\"id\":\"dataLayer-UA-36759908-1\",\"lazy\":false,\"lazyType\":\"both\",\"debugMessage\":\"Data Layer UA-36759908-1\"},{\"text\":\"n      \/\/ Define the gtag() APIn      window.dataLayer = window.dataLayer || [];n      function gtag(){dataLayer.push(arguments)};nn      \/\/ Define fbq() APIn      !function (f, b, e, v, n, t, s) {n        if (f.fbq) return; n = f.fbq = function () {n          n.callMethod ?n            n.callMethod.apply(n, arguments) : n.queue.push(arguments)n        };n        if (!f._fbq) f._fbq = n; n.push = n; n.loaded = !0; n.version = '2.0';n        n.queue = []; t = b.createElement(e); t.async = !0;n        t.src = v; s = b.getElementsByTagName(e)[0];n        s.parentNode.insertBefore(t, s)n      }(window, document, 'script',n        'https:\/\/connect.facebook.net\/en_US\/fbevents.js');nn      \/\/ Call default commands with static settings to fall back on.n      \/\/ Consent commands must appear before gtag.js or Google Tag Manager is loadedn      gtag('consent', 'default', {n        'ad_storage': 'denied',n        'analytics_storage': 'granted',n        'wait_for_update': 500n      });nn      const facebookPixelsData = [{\"name\":\"analytics\",\"codeId\":\"UA-27070218-1\",\"events\":false},{\"name\":\"fbPixel\",\"codeId\":\"1677839712495774\",\"events\":false},{\"name\":\"fbPixel\",\"codeId\":\"642083852878423\",\"events\":false},{\"name\":\"analytics\",\"codeId\":\"UA-36759908-1\",\"events\":true}];nn      for (let index = 0; index < facebookPixelsData.length; index++) {n        if (!facebookPixelsData[index].name || facebookPixelsData[index].name === 'fbPixel') {n          \/\/ Init fbPixeln          fbq('init', facebookPixelsData[index].codeId, {});n          fbq('track', 'PageView');n        }n      }nn      \/\/ Revoke consent fbPixeln      fbq('consent', 'revoke');nn      window.didomiOnReady = window.didomiOnReady || [];n      window.didomiOnReady.push(function (Didomi) {n        gtag('consent', 'update', {n          'ad_storage': Didomi.getUserConsentStatusForVendor('google') ? 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