- Index hide
According to Statista, in February 2022, it was estimated that around 14.1 million adults in Mexico suffered from diabetes.
According to Statista, in 2019, there were 21.6 deaths from diabetes mellitus per 100,000 population in the United States.
Researchers have published encouraging findings from a recent cell therapy experiment for diabetics. The potential of a new cell therapy for the treatment of adults with type 2 diabetes and increased kidney damage despite receiving the best medical care.
What is the research on cell therapy to reduce kidney damage from diabetes?
The NEPHSTROM clinical trial is beginning to investigate the potential of a new cell therapy for the treatment of adults with type 2 diabetes and increasing kidney damage despite receiving the best medical care.
Results from the NEPHSTROM clinical trial were presented in November at the American Nephrology Society Kidney Week in Orlando, showing that a single dose of ORBCEL-M, administered intravenously to carefully selected adults with worsening kidney disease due to diabetes, was safe and was associated with better preservation of renal function compared with placebo.
How was the study carried out?
Patients participating in the trial were closely followed for 18 months after receiving ORBCEL-M. ORBCEL-M Cell Therapy is a mesenchymal stromal cell preparation made from healthy bone marrow that was discovered and developed in Galway by Orbsen Therapeutics Ltd, a spin-off company of the University of Galway.
The clinical trial is run from the IRCCS Mario Negri Institute for Pharmacological Research in Bergamo in Italy and is being carried out jointly at leading medical centers in Galway, Bergamo, Birmingham and Belfast.
Professor Matt Griffin, Principal Investigator at the Institute for Regenerative Medicine at the University of Galway, said: “Almost a quarter of a million Irish people have diabetes and we know that more than 40% of them have symptoms of kidney disease, often referred to as kidney disease. diabetic or DKD, for its acronym in English.”
“In the case of type 2 diabetes, up to a third of people with DKD have worsening kidney function despite the best medical treatment we can offer. These people are at high risk of needing dialysis or a kidney transplant in the coming years, two complex treatments with potentially serious complications.”
Related notes: